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The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus.

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To date, a few cases of overdose (maximum: 2000 mg) with bisoprolol fumarate have been reported.

Children: The safety and effectiveness of bisoprolol in children and adolescents is not determined.

Diarrhea occurred as a dose-related event.

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If you are to take it once a day, take it in the morning; if you are to take it twice a day, take it in the morning and in the late afternoon to avoid going to the bathroom during the night.

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The medical and family history help the physician determine if the patient has any conditions or disorders that might contribute to or cause the hypertension.

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Green tea is extremely high in vitamin K and small amounts of green tea can cause complications.

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We thank all patients who participated in CIBIS III, as well as the study investigators (see the Appendix in the online-only Data Supplement), members of the Data Safety Monitoring Board and the End Point Committee (see Appendix), study nurses, and coordinators, whose work made the trial possible.

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In the specific case of bisoprolol manufacture the key oxazolidinone benzaldehyde intermediate may also be prepared in a "telescoped" process described in this example 3, this process is more efficient as the use of MTBE for the isolation of oxazolidinone sulphonate is eliminated.

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Xanthine-containing food or beverages and fruit juices were not allowed for 24 hours before and during the entire sampling days.

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At high doses, bisoprolol is less cardioselective and can induced acute bronchospasm.

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These hazards include fetal or neonatal jaundice, pancreatitis, thrombocytopenia, and possibly other adverse reactions that have occurred in the adult.

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Conclusions Preservation of left ventricular function appears to play a key role in the bisoprolol-induced beneficial effects on prognosis in heart failure.

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